Srinivas Malladi, Ph.D.
Srinivas Malladi, Ph.D.
The University of Texas Southwestern Medical Center
Titles & Positions

  • Assistant Professor, Department of Pathology

Institutional & Related Links

Profile

Biography

Grant Information

Grant ID: RR170003
Grant Mechanism: 
Recruitment of First-Time, Tenure-Track Faculty Members
Recruited From: 
Memorial Sloan-Kettering Cancer Center
Date Awarded: 
November 16, 2016
Grant Amount: 
$2,000,000

Srinivas obtained his Ph.D. from The University of Texas at Austin and then joined Memorial Sloan Kettering Cancer Center as an American Cancer Society Fellow with Dr. Joan Massague.  At MSKCC, he developed novel models of lung and breast adenocarcinomas to study metastatic latency. Latent metastasis is the least studied and decisive phase of the metastatic cascade.  Cancer cells in this state are resistant to conventional or targeted therapies that are directed towards proliferating cancer cells.

Therefore, identifying cellular and molecular determinants of metastatic latency will open a major untapped opportunity to prevent metastasis. Dr. Malladi’s lab in the Department of Pathology is focused on understanding how disseminated cancer cells survive and give rise to metastasis at a cellular and molecular level using an integrated approach.