|Awarded On||August 21, 2019|
|Title||The Dissemination of a Genetic Navigation Framework for Hereditary Cancers to Increase Mutation Carrier Identification and Improve Outcomes|
|Award Mechanism||Dissemination of CPRIT-Funded Cancer Control Interventions|
|Institution/Organization||The University of Texas Southwestern Medical Center|
|Principal Investigator/Program Director||Theodora Ross|
|Cancer Sites||Breast, Colorectal, Ovary, Uterus|
*Pending contract negotiation
Need: There is a need to determine Texans that would benefit from genetic counseling and testing as outlined in the 2018 Texas Cancer Plan. Overall, 76,600 Texans are projected to be mutation carriers for Hereditary Breast and Ovarian Cancer Syndrome (HBOC) or Lynch Syndrome (LS), the two most common hereditary cancer conditions with Tier 1 designation. Over half of these individuals have or will develop cancer. In screening the mammography patients for HBOC, we reported that 60% of underserved and 33% of insured patients identified had a prior diagnosis of breast cancer but no testing offered before diagnosis. This population represents a distinct opportunity to reduce cancer incidence, as ...