Grant ID RP120190
Awarded On November 02, 2011
Title Oncometabolites in Renal Cancer
Program Academic Research
Award Mechanism High Impact/High Risk
Institution/Organization The University of Texas Health Science Center at San Antonio
Principal Investigator/Program Director Karen Block
Cancer Sites Kidney and Renal Pelvis
Contracted Amount $199,902
Lay Summary

Renal Cancer is among the 10 most common malignancies in both men and women. Despite the recent approval of new therapies to target this malignancy, the reality is that most patients with advanced disease will not survive (median survival 13 months). Hence, the elucidation of novel molecular mechanisms is needed to develop more effective therapies for this deadly disease. Increasing evidence supports the paradigm that cancer development is tightly linked to alterations in metabolism. Metabolism refers to the complex set of chemical reactions that are required by an organism to conduct the basic processes required for survival. As a result, our laboratory has performed a comprehensive me...

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