Grant ID RP120611
Awarded On November 02, 2011
Title Small Animal Cancer Imaging Core
Program Academic Research
Award Mechanism Core Facility Support Awards
Institution/Organization The University of Texas Medical Branch at Galveston
Principal Investigator/Program Director Massoud Motamedi
Cancer Sites All Sites
Contracted Amount $578,204
Lay Summary

Molecular imaging is a powerful diagnostic tool that can be used to visualize and target tumors in small animal models enabling cancer researchers to assess the efficacy of new diagnostic and therapeutic strategies in preclinical models prior to translation to the clinic. Bioluminescence and fluorescence imaging is a high sensitivity and high throughput molecular optical imaging modality for whole body small animal imaging where it is now possible to use genes encoding luciferase and fluorescent proteins that can be engineered into cells and small animal models enabling cells produce light that can then be visualized through the tissues in living animal. The objective of this proposal...

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