Grant ID RP120613
Awarded On November 02, 2011
Title Develop cutting-edge proteomics core facility based on high resolution, high accuracy mass spectrometry and high throughput, web-based bioinformatics technology
Program Academic Research
Award Mechanism Core Facility Support Awards
Institution/Organization The University of Texas Southwestern Medical Center
Principal Investigator/Program Director Hamid Mirzaei
Cancer Sites All Sites
Contracted Amount $4,400,000
Lay Summary

Cancer cells function differently from normal cells in order to accommodate their abnormal needs for rapid growth, reproduction, spreading etc. Proteins are in many ways responsible for allowing cancer cells to assume their destructive biology. Cells like large cities have complicated communication systems. In cancer cells, these communication systems are altered. Alteration of these communication systems can be accomplished by altering protein concentrations or modification patterns. Detecting these differences allows scientists to find the altered communication routes which could then be used to: 1) devise new strategies to battle cancer; or 2) provide new ways to detect cancer at its earl...

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