Grant ID RP120617
Awarded On November 02, 2011
Title Advanced in vivo imaging of tumor initiation and progression
Program Academic Research
Award Mechanism Core Facility Support Awards
Institution/Organization University of Houston
Principal Investigator/Program Director Jan-Ake Gustafsson
Cancer Sites All Sites
Contracted Amount $990,286
Lay Summary

Research on the interactions of tumors with their local tissue environment requires live animal assays to fully understand the process of cancer progression. Recognizing this need, researchers have made significant progress in the noninvasive imaging of animal models of cancer. By imaging the animal at multiple time points, we can better understand disease pathology, pharmacokinetics and other contextual aspects of the molecular processes taking place in the living animal. Additionally, in whole-animal imaging, each animal serves as its own statistical control, which improves the statistical quality of the data and thus reduces the required number of animals. At the forefront of this technol...

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