|Awarded On||December 05, 2012|
|Title||Minimally-invasive intratumoral drug delivery using micronedles to treat oral squamous carcinomas|
|Award Mechanism||High Impact/High Risk|
|Institution/Organization||Texas Tech University|
|Principal Investigator/Program Director||Harvinder S Gill|
|Cancer Sites||Head and Neck|
An estimated 40,250 new cases of oral cavity tumors will be diagnosed in the US in 2012 and 7,850 people will die of the disease. Tumor of the tongue accounts for over 60% of oral tumors. The goal of this research is to develop a minimally invasive method of treating tongue tumor and other tumors of the mouth without use of surgery because surgical removal of tongue and mouth tissue often results in severe swallowing, eating, speech, cosmetic and psychological disabilities among the patients. Furthermore, over the last 30 years, aggressive surgical treatment has not resulted in any significant improvement in the five-year survival rates. Overall, there is lack of a treatment approach that ca...