Grant ID RP130293
Awarded On December 05, 2012
Title Minimally-invasive intratumoral drug delivery using micronedles to treat oral squamous carcinomas
Program Academic Research
Award Mechanism High Impact/High Risk
Institution/Organization Texas Tech University
Principal Investigator/Program Director Harvinder S Gill
Cancer Sites Head and Neck
Contracted Amount $199,910
Lay Summary

An estimated 40,250 new cases of oral cavity tumors will be diagnosed in the US in 2012 and 7,850 people will die of the disease. Tumor of the tongue accounts for over 60% of oral tumors. The goal of this research is to develop a minimally invasive method of treating tongue tumor and other tumors of the mouth without use of surgery because surgical removal of tongue and mouth tissue often results in severe swallowing, eating, speech, cosmetic and psychological disabilities among the patients. Furthermore, over the last 30 years, aggressive surgical treatment has not resulted in any significant improvement in the five-year survival rates. Overall, there is lack of a treatment approach that ca...

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