Grant ID RP130368
Awarded On December 05, 2012
Title Proton Beam Radiation Therapy vs. Conventional Beam Radiation Therapy: Toxicities During & After Craniospinal Radiation Therapy in Children (Carson Leslie Award)
Program Academic Research
Award Mechanism Individual Investigator
Institution/Organization Baylor College of Medicine
Principal Investigator/Program Director M Douglas Ris
Cancer Sites Brain and Other Nervous System
Contracted Amount $1,189,121
Lay Summary

The number of survivors of pediatric brain tumors has greatly increased in the past two decades making it apparent that many are left with life-long physical and neurodevelopmental impairments secondary to life-saving treatments (particularly radiotherapy) received for their disease. An emerging radiotherapy technology using protons (Proton Beam Radiation Therapy; PBRT) rather than conventional photons or x-rays promises to reduce toxicity burden and improve outcomes and quality of life in survivors. Many herald the clinical potential of PBRT to minimize damage to healthy brain tissue and other organs of the body without sacrificing disease control. Still, there are no published reports t...

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