Grant ID RP140252
Awarded On August 20, 2014
Title Investigating and Preclinical Targeting Molecular Drivers of Muscle-Invasive Bladder Cancer
Program Academic Research
Award Mechanism Individual Investigator
Institution/Organization Baylor College of Medicine
Principal Investigator/Program Director Keith Chan
Cancer Sites Bladder
Contracted Amount $827,451
Lay Summary

Bladder cancer is the fifth most common cancer and the most expensive cancer to treat (i.e. cost per patient) in the United States. In the past thirty years, there has been no major improvement in the survival of patients with muscle-invasive bladder cancer, since surgical removal of the entire bladder and chemotherapy still remain the major treatment options. Thus far, no specific therapy other than conventional therapy (e.g. chemotherapy, radiation) is clinically approved to treat invasive bladder cancer, since the genetic causes for invasion remains largely unknown. While other possible genetic causes were intensively studied and shown to be associated with human invasive bladder cancers ...

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