Grant ID RP140262
Awarded On August 20, 2014
Title Intrinsic Reward Sensitivity & Smoking Cessation with Varenicline or Patch NRT
Program Academic Research
Award Mechanism Individual Investigator
Institution/Organization The University of Texas M.D. Anderson Cancer Center
Principal Investigator/Program Director Paul M Cinciripini
Cancer Sites Bladder, Cervix Uteri, Head and Neck, Leukemia, Lung and Bronchus, Pancreas
Contracted Amount $899,505
Lay Summary

Cigarette smoking is still the major cause of preventable disease in the United States. The proposed research is relevant to public health because it proposes to develop a measure of brain activity that will help determine which smokers are more likely to benefit from varenicline or nicotine replacement therapy, prior to their receiving the drug. The medications have different levels of effectiveness and different side effects. Knowing which one works best for each person will help improve overall cessation since smokers would get the most effective treatment with the fewest side effects, based on the measure of brain activity we take before treatment begins.