Grant ID RP150195
Awarded On February 18, 2015
Title Mechanisms of DHA and EPA differential effects on colon cancer chemoprevention
Program Academic Research
Award Mechanism Individual Investigator Research Awards for Prevention and Early Detection
Institution/Organization The University of Texas M.D. Anderson Cancer Center
Principal Investigator/Program Director Imad Shureiqi
Cancer Sites Colorectal
Contracted Amount $920,926
Lay Summary

Colon cancer is the second most common cause of cancer death in the United States. Despite progress in prevention and treatment of colon cancer, the 5-year death rate from this disease remains almost 40%. Clearly, better measures to treat and prevent colon cancer are needed. Improved understanding of the mechanisms underlying the formation of colon cancer will provide key information needed to develop new preventive measures for this commonly fatal disease. Fish oil and its omega-3 fatty acid derivatives eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) have been widely promoted to prevent chronic diseases. However, the effects of fish oil and DHA and EPA have been inconsistent in ...

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