|Awarded On||May 20, 2015|
|Title||Metabolomic Salivary Biomarkers for Oral Cancer Detection|
|Award Mechanism||High Impact/High Risk|
|Institution/Organization||Texas A&M University System Health Science Center|
|Principal Investigator/Program Director||Yi-Shing Cheng|
|Cancer Sites||Head and Neck|
With advances in cancer detection and treatment, the survival rate for many cancers has greatly improved, but the rate for oral cancer remains low; about 40% of oral cancer patients die within 5 years, usually because it is not diagnosed until already at an advanced stage. Thus, we urgently need to detect oral cancer earlier. Because constituents of human saliva have been found to reflect the body’s physiological state, analyzing saliva holds promise as an easy way to test for oral cancer. Research has identified more than 100 salivary constituents that could help to detect oral cancer. These “potential salivary biomarkers” are constituents that have shown significantly different levels in o...