Grant ID RP190022
Awarded On February 21, 2019
Title A Randomized, Controlled Trial Comparing the Immunogenicity of 2 Doses Versus 3 Doses of the 9-Valent HPV Vaccine in Males and Females 15 to 26 Years of Age
Program Academic Research
Award Mechanism Individual Investigator Research Awards for Prevention and Early Detection
Institution/Organization The University of Texas Medical Branch at Galveston
Principal Investigator/Program Director Abbey Berenson
Cancer Sites Cervix Uteri, Head and Neck, Penis
Contracted Amount $1,491,473*

*Pending contract negotiation

Lay Summary

The HPV vaccine is recommended for all adolescents and young adults to prevent several types of cancer. If the vaccine series is started by 14 years of age, only 2 doses are recommended. However, if the vaccine series is started at age 15 or greater, 3 doses are recommended. It is possible that 2 doses are actually sufficient in older teens and young adults, but no one has tested this hypothesis to see if it is true. We will conduct a clinical trial to examine the immune response of older teens and young adults who receive 3 doses of the HPV vaccine as compared to the immune response of those who receive only 2 doses. We hypothesize that the immune responses will be similar, demonstrating th...

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