Grant ID RP200233
Awarded On February 19, 2020
Title Advance CT And Fluorescence Imaging Of Kidney Cancers With Glutathione-mediated Contrast Enhancements
Program Academic Research
Award Mechanism Individual Investigator
Institution/Organization The University of Texas at Dallas
Principal Investigator/Program Director Jie Zheng
Cancer Sites Kidney and Renal Pelvis
Contracted Amount $900,000*

*Pending contract negotiation

Lay Summary

With more and more kidney cancers being diagnosed in the early stage, partial nephrectomy is becoming an increasingly important treatment for kidney cancers, in particular for those patients who have poor kidney function or cancer on both kidneys. In the current clinical settings, X-ray computerized tomography (CT) is utilized first to noninvasively localize and stage the kidney cancers, followed by fluorescently imaging normal renal parenchyma to in situ guide partial nephrectomy. However, due to the limitations of current contrast agents for X-ray CT and fluorescence imaging of kidney cancers, hundreds of clinical case studies have shown that introducing clinically approved near infrared d...

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