|Awarded On||February 16, 2022|
|Title||Implementation of Cancer Screening in Children and Adolescents Genetically at High Risk of Cancer|
|Award Mechanism||Individual Investigator Research Awards for Prevention and Early Detection|
|Institution/Organization||The University of Texas Health Science Center at San Antonio|
|Principal Investigator/Program Director||G. E. Tomlinson|
|Cancer Sites||All Sites|
There are currently over 50 known genetic syndromes associated with a high risk of cancer in children and adolescents. Identifying children at high risk of cancer is based on physical features, family history, and often is confirmed by genetic testing. Although there is much known about the application of follow-up screening guidelines for the common adult cancers such as breast or colon cancer in individuals wit genetic risks, there is much less known about screening for cancer in children determined to have a high risk of cancer.
Moreover, published evidence for surveillance for cancer in high-risk children is largely from studies at large academic centers and there is much less informat...