Grant ID RP220599
Awarded On September 14, 2022
Title Texas Pediatric Cancer Testing (TPCT) Core
Program Academic Research
Award Mechanism Core Facility Support Awards
Institution/Organization The University of Texas Health Science Center at San Antonio
Principal Investigator/Program Director Peter J Houghton
Cancer Sites Gallbladder, Leukemia, Liver and Intrahepatic Bile Duct, Sarcoma
Contracted Amount $3,935,480*

*Pending contract negotiation

Lay Summary

Despite some advances, the long-term disease control in many children remains elusive; improved survival has been largely driven by dose escalation and introduction of new agents, but in many survivors, these therapies are coupled to long-term life-threatening sequelae. New therapeutics are desperately needed. Increased understanding of the molecular pathology for many childhood cancers, and growing awareness that 'homogeneous' diseases are in fact heterogeneous at a molecular level provide basis for identification of agents targeted at specific molecular drivers and development of effective therapeutics. This Core will provide a service for testing new agents/combinations, against a large p...

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