|Awarded On||November 20, 2019|
|Title||Recruitment of First-Time, Tenure-Track Faculty Members|
|Award Mechanism||Recruitment of First-Time, Tenure-Track Faculty Members|
|Institution/Organization||The University of Texas Southwestern Medical Center|
|Principal Investigator/Program Director||Matteo Ligorio|
|Cancer Sites||Gallbladder, Liver and Intrahepatic Bile Duct, Pancreas|
|Summary of Goals and Objectives||
Pancreatic cancer (PDAC) is the fourth leading cause of cancer deaths and is rising in this category, despite significant progress. This prognosis makes these tumors a public health problem as well as a constant challenge for doctors who treat this aggressive disease.
During my surgical training I operated on PDAC patients and from these experiences decided to become a physician-scientist in an effort to find novel therapeutic strategies directed towards this disease. This proposal is the logical next step based on my research training, in which we found that tumor architecture is an important factor involved in tumor evolution.